The Benefits of MSM in Skincare: What Science Says

The Benefits of MSM in Skincare: What Science Says

When it comes to skincare, there’s always a surge in interest around ingredients that promise to deliver multiple benefits for skin health. One such ingredient is MSM (methylsulfonylmethane), a naturally occurring sulfur compound known for its anti-inflammatory, antioxidant, and collagen-boosting properties. With studies increasingly pointing to its effectiveness, MSM has become a favorite in many skincare products. In this blog post, we’ll explore the science behind MSM and how it benefits the skin.

What is MSM?

MSM is an organic sulfur compound found naturally in plants, animals, and humans. It plays an essential role in the body, particularly in the synthesis of collagen and keratin—two key proteins that keep our skin, hair, and nails strong and healthy. MSM is often used as a supplement for its anti-inflammatory properties and is increasingly incorporated into skincare products for its ability to promote healthier skin.

1. Reduces Inflammation and Redness

One of MSM’s most well-known benefits is its ability to reduce inflammation. Inflammation plays a central role in many skin conditions, including acne, rosacea, and eczema. A study published in the Journal of Drugs in Dermatology found that MSM applied topically helped reduce redness and inflammation in patients with rosacea, a condition that causes persistent facial redness. This is significant because persistent inflammation can lead to long-term damage and aging in the skin, but MSM’s ability to calm inflammation can mitigate this.

2. Supports Collagen Production

Collagen is the protein responsible for keeping skin firm and youthful. As we age, our natural collagen production decreases, leading to wrinkles and sagging skin. MSM can help support collagen synthesis, which is crucial for maintaining skin elasticity. A 2015 study in the National Institutes of Health found that MSM supplementation improved the appearance of fine lines and wrinkles by enhancing collagen production. This makes MSM an excellent ingredient for anyone looking to keep their skin plump and youthful.

3. Improves Skin Hydration

Dry skin is a common issue for many people, especially in colder months. MSM has been shown to improve skin hydration by enhancing the skin's ability to retain moisture. A study published in the Journal of Cosmetic Dermatology found that topical application of MSM resulted in increased skin hydration and moisture retention, making it a great ingredient for anyone looking to achieve a more dewy and nourished complexion.

4. Reduces Hyperpigmentation and Dark Spots

MSM’s role in promoting healthy skin doesn’t stop at hydration and collagen production—it may also help reduce hyperpigmentation. Some studies suggest that MSM can lighten dark spots, sun damage, and hyperpigmentation, especially when combined with other brightening ingredients like vitamin C. A study from Antioxidants journal showed that MSM has a depigmenting effect on skin and can help even out skin tone.

5. Heals and Repairs Skin Damage

MSM's natural healing properties also make it effective in promoting the repair of damaged skin. For individuals with acne scars or wounds, MSM can speed up the healing process and reduce the appearance of scars. In fact, studies suggest that MSM may encourage the repair of skin tissues and promote faster healing by stimulating the production of key molecules that support skin repair. Research in the Journal of Clinical and Aesthetic Dermatology revealed that MSM supplementation accelerated wound healing and improved the appearance of post-acne scars.

6. Antioxidant Protection Against Environmental Stress

Free radicals, generated by UV exposure, pollution, and environmental toxins, contribute to premature aging and skin damage. MSM acts as an antioxidant, helping to neutralize these free radicals. Research published in the International Journal of Molecular Sciences found that MSM can help protect skin cells from oxidative stress, thus reducing the impact of environmental stressors on the skin. This makes MSM a valuable ingredient in anti-aging skincare formulations.

How to Use MSM in Your Skincare Routine

MSM can be found in various skincare products, including creams, serums, masks, and oils. For optimal results, choose a product that combines MSM with other beneficial ingredients, such as vitamin C for brightening or hyaluronic acid for hydration.

  • Topical Application: Look for MSM-enriched moisturizers or serums that can be applied directly to the skin after cleansing.
  • Supplements: You can also take MSM supplements to support skin health from within. However, always consult a healthcare professional before starting any supplementation regimen.

The evidence supporting MSM in skincare is mounting, with studies highlighting its ability to reduce inflammation, support collagen production, improve hydration, and promote skin healing. Whether you’re struggling with redness, acne scars, or fine lines, MSM is a versatile and effective ingredient to incorporate into your skincare routine. As always, make sure to patch-test any new products and consult with a dermatologist if you have concerns.

By harnessing the power of MSM, you can help your skin maintain its natural radiance, strength, and youthful appearance—naturally.


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MISMO MSM - 440g / Ultra-Pure Distilled - Pain Relief
MISMO MSM - Pain Relief
MISMO MSM - Capsules / Ultra-Pure Distilled - Pain Relief
MSM capsules pain relief
MISMO MSM - 440g / Pure Crystalline - Pain Relief
MISMO MSM - 850g Ultra-Pure Distilled - Pain Relief
MISMO MSM - 850g/ Pure Crystalline - Pain Relief
MISMO MSM - 2kg Ultra-Pure Distilled - Pain Relief
MISMO MSM - 2kg / Pure Crystalline - Pain Relief
MISMO MSM - Capsules/ Ultra-Pure Distilled - Pain Relief
MISMO MSM - Capsules / Ultra-Pure Distilled - Pain Relief

MISMO MSM

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Relieves arthritis pain and stiffness – Reduces inflammation and improves flexibility for easier movement.

✅ Supports cartilage and joint health – Helps rebuild and strengthen joints for long-term mobility.

✅ Boosts skin hydration and elasticity – Protects collagen and prevents wrinkles for firmer, healthier skin.

Strengthens hair and nails – Encourages strong, healthy growth while preventing brittleness.

✅ Aids muscle recovery and reduces soreness – Helps repair tissues and ease post-workout discomfort.

✅ Supports gut health and digestion – Helps repair the gut lining, reducing bloating and improving nutrient absorption.

Why it works: MSM is a natural source of sulfur, which your body needs to keep joints flexible, reduce inflammation, and support healthy skin, hair, and nails. It helps rebuild cartilage, strengthens connective tissue, and protects collagen, making movement easier and keeping your skin firm and hydrated. Since MSM is lost in food processing, supplementing restores these essential benefits for better mobility, less pain, and overall vitality.

Who is it for? Anyone looking for natural arthritis relief, improved joint health, stronger hair and nails, or enhanced skin and gut function. 

How does MSM help with arthritis and joint pain?

  • Reduces inflammation – Helps ease joint pain and stiffness for better movement.
  • Supports cartilage and flexibility – Provides sulfur for strong, healthy joints.
  • Improves mobility – Helps you move with less discomfort so you can stay active.

Many people with arthritis, osteoarthritis, and joint pain find that daily MSM supplementation makes a noticeable difference in their comfort and movement.

MSM for Skin, Hair, and Nails

  • Helps protect and restore collagen, reducing fine lines and wrinkles.
  • Strengthens hair and nails, preventing brittleness and breakage.
  • Boosts glutathione, a key antioxidant that fights pigmentation and sun damage.
  • Improves skin hydration, keeping skin soft, clear, and healthy.

MSM for Exercise Recovery

  • Helps reduce muscle soreness and inflammation after workouts.
  • Speeds up tissue repair, helping muscles and joints recover faster.
  • Supports athletes, gym-goers, and active lifestyles by preventing injuries.

Active Ingredients

100% MSM (Methylsulfonylmethane) – A bioavailable, ultra-pure form of sulfur that supports joint health, reduces inflammation, and strengthens hair, skin, and nails.

Packaged in Australia from imported ingredients. Vegan, gluten-free, and free from additives or anti-caking agents.

How to Use

  • Start small: Take ¼–½ teaspoon per day (or 1–2 capsules) to avoid detox effects.
  • Increase gradually: After a week, slowly increase to 2–6 grams daily (5–6 capsules), adjusting based on your needs.

Best taken in the morning: Many find it gives a natural energy boost. Mix with water or juice.

If detox symptoms like headaches occur, reduce the dose and build up slowly.

WARNINGS: If taking strong blood thinners, do not take MSM without your doctor's approval. Not to be taken by children without a health professional's advice.  MSM can also interfere with the accuracy of the blood test for liver enzymes by sometimes producing false positive results. It is recommended you cease taking MSM at least 4 days before these blood tests. You can resume after the test.

How much MSM should I take daily?

  • Start small: ¼–½ teaspoon (or 1–2 capsules) to allow your body to adjust.
  • Increase slowly: Most people take around 1 teaspoon daily (4g).
  • Higher doses may provide extra relief—adjust based on how you feel.

Should I choose MSM capsules or powder?

MSM Powder is the most cost-effective option for daily use at home. It is the best option for those on a larger dose (2tsp+).

MSM Capsules are convenient for travel and great for those who don’t like the taste of MSM powder.

Where does MISMO MSM come from?

MISMO MSM is tested for purity and quality, ensuring you get a clean, bioavailable supplement.

There are two types of MSM:

  • Distilled Ultra-Pure MSM – The gold standard, made using a 4-step distillation process for the purest form.
  • Pure-Crystalline MSM – Created through a centrifuge process, maintaining high purity while being slightly more affordable.

Every batch is independently tested to ensure zero additives, fillers, or anti-caking agents.

Click here for a detailed explanation of how MSM is manufactured.

What is the science of MSM?

Sulfur is essential for keeping your skin firm, joints flexible, and connective tissue strong. MSM provides a natural source of sulfur, helping your body produce collagen and elastin—the key proteins that keep skin smooth and resilient. Nearly half of your body's sulfur is found in your skin, muscles, cartilage, and bones, making it crucial for overall strength and mobility.

Click here for more information on The Science of MSM

    Is MISMO MSM listed with the TGA (Therapeutic Goods Administration)?

    Yes, click here to view the TGA listing for MISMO MSM

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