How Does MSM Promote Collagen and Keratin Production?

How Does MSM Promote Collagen and Keratin Production?

MSM is an organic sulfur compound, found naturally in plants, animals, and even humans, has been gaining recognition for its remarkable ability to promote collagen and keratin production – two essential proteins that play crucial roles in maintaining our youthful appearance and general well-being.

MSM and Collagen

Collagen is often referred to as the "glue" that holds our bodies together. It is the most abundant protein in the human body, providing structural support to our skin, bones, tendons, and cartilage. As we age, our body's ability to produce collagen reduces significantly, leading to wrinkles, joint pain, and other age-related issues. MSM is a one-stop-shop for counteracting these effects and here's why.

MSM works by providing the necessary sulfur compounds required for collagen synthesis. Sulfur is an essential mineral for the formation of disulfide bonds, which are crucial for the stability and strength of collagen fibers. By increasing the body's sulfur levels, MSM can enhance collagen production, leading to healthier, more youthful-looking skin, stronger bones, and improved joint health.

MSM and Keratin

While collagen is the glue that holds us together, keratin is the protein that gives our hair, nails, and skin their strength and resilience. Like collagen, keratin production also requires sulfur compounds, which MSM can provide in abundance.

Hair and Keratin

Hair is composed of 95% keratin, a fibrous, helicoidal protein that is a component of the skin and its appendages, including the hair and nails. It is synthesized by keratinocytes and is insoluble in water, which helps to protect the hair and contributes to its impermeability.

The hair contains 18 amino acids, including proline, threonine, leucine, and arginine. Keratin is particularly rich in cysteine. Cysteine is a sulfurated amino acid that forms disulfide bonds between molecules and thus lends the structure strength and resistance. Aging and excessive exposure of hair to solar irradiation cause dryness, reduced strength, a rough surface texture, loss of color, decreased luster, stiffness, brittleness, and an overall dull, unhealthy appearance.

Studies have shown that MSM can improve keratin production, resulting in stronger, healthier hair and nails that are less prone to breakage and splitting. MSM works by providing the necessary sulfur compounds for keratin synthesis, enabling the formation of disulfide bonds that contribute to the strength and durability of keratin fibers.

Nails and Keratin

Nails are composed of a protective protein called alpha-keratin, which imparts tough rigidity. Nails get their strength from 3 linked keratin layers, where oils and moisture cement and lubricate the nail plate. Functionality results from the nail shape, which mirrors that of the underlying bone. Hair and nails that maintain tight inter-corneocyte connections are generally not subject to desquamation. However, hair is shed through life-cycle programming, and nail corneocytes are eroded due to friction and physical activity.

"MSM may donate sulfur to keratin, which could help strengthen the bonds between keratin molecules in the hair and nails."

By promoting collagen and keratin production, MSM offers a range of potential benefits that extend far beyond just healthy skin and hair:

  1. Improved Skin Health: Increased collagen production can lead to firmer, more elastic skin with fewer wrinkles and fine lines, giving you a radiant, youthful glow.
  2. Stronger Bones and Joints: Collagen is essential for maintaining bone density and joint health, reducing the risk of osteoporosis and joint degeneration. With MSM supporting collagen production, you can enjoy greater mobility and flexibility as you age.
  3. Healthier Hair and Nails: Boosted keratin production can result in stronger, more resilient hair and nails, reducing breakage and promoting growth. Say goodbye to split ends and brittle nails!
  4. Faster Wound Healing: Collagen plays a crucial role in the wound healing process, and increased collagen production can accelerate tissue repair, helping you recover from injuries more quickly.
  5. Reduced Inflammation: MSM has been shown to possess anti-inflammatory properties, which can help alleviate joint pain, muscle soreness, and other inflammatory conditions.

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MISMO MSM

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✅ Relieves arthritis pain and stiffness – Reduces inflammation and improves flexibility for easier movement.

✅ Supports cartilage and joint health – Helps rebuild and strengthen joints for long-term mobility.

✅ Boosts skin hydration and elasticity – Protects collagen and prevents wrinkles for firmer, healthier skin.

✅ Strengthens hair and nails – Encourages strong, healthy growth while preventing brittleness.

✅ Aids muscle recovery and reduces soreness – Helps repair tissues and ease post-workout discomfort.

✅ Supports gut health and digestion – Helps repair the gut lining, reducing bloating and improving nutrient absorption.

Why it works: MSM is a natural source of sulfur, which your body needs to keep joints flexible, reduce inflammation, and support healthy skin, hair, and nails. It helps rebuild cartilage, strengthens connective tissue, and protects collagen, making movement easier and keeping your skin firm and hydrated. Since MSM is lost in food processing, supplementing restores these essential benefits for better mobility, less pain, and overall vitality.

Who is it for? Anyone looking for natural arthritis relief, improved joint health, stronger hair and nails, or enhanced skin and gut function. 

How does MSM help with arthritis and joint pain?

  • Reduces inflammation – Helps ease joint pain and stiffness for better movement.
  • Supports cartilage and flexibility – Provides sulfur for strong, healthy joints.
  • Improves mobility – Helps you move with less discomfort so you can stay active.

Many people with arthritis, osteoarthritis, and joint pain find that daily MSM supplementation makes a noticeable difference in their comfort and movement.

MSM for Skin, Hair, and Nails

  • Helps protect and restore collagen, reducing fine lines and wrinkles.
  • Strengthens hair and nails, preventing brittleness and breakage.
  • Boosts glutathione, a key antioxidant that fights pigmentation and sun damage.
  • Improves skin hydration, keeping skin soft, clear, and healthy.

MSM for Exercise Recovery

  • Helps reduce muscle soreness and inflammation after workouts.
  • Speeds up tissue repair, helping muscles and joints recover faster.
  • Supports athletes, gym-goers, and active lifestyles by preventing injuries.

Active Ingredients

100% MSM (Methylsulfonylmethane) – A bioavailable, ultra-pure form of sulfur that supports joint health, reduces inflammation, and strengthens hair, skin, and nails.

Packaged in Australia from imported ingredients. Vegan, gluten-free, and free from additives or anti-caking agents.

How to Use

  • Start small: Take ¼–½ teaspoon per day (or 1–2 capsules) to avoid detox effects.
  • Increase gradually: After a week, slowly increase to 2–6 grams daily (5–6 capsules), adjusting based on your needs.

Best taken in the morning: Many find it gives a natural energy boost. Mix with water or juice.

If detox symptoms like headaches occur, reduce the dose and build up slowly.

WARNINGS: If taking strong blood thinners, do not take MSM without your doctor's approval. Not to be taken by children without a health professional's advice.  MSM can also interfere with the accuracy of the blood test for liver enzymes by sometimes producing false positive results. It is recommended you cease taking MSM at least 4 days before these blood tests. You can resume after the test.

How much MSM should I take daily?

  • Start small: ¼–½ teaspoon (or 1–2 capsules) to allow your body to adjust.
  • Increase slowly: Most people take around 1 teaspoon daily (4g).
  • Higher doses may provide extra relief—adjust based on how you feel.

Should I choose MSM capsules or powder?

MSM Powder is the most cost-effective option for daily use at home. It is the best option for those on a larger dose (2tsp+).

MSM Capsules are convenient for travel and great for those who don’t like the taste of MSM powder.

Where does MISMO MSM come from?

MISMO MSM is tested for purity and quality, ensuring you get a clean, bioavailable supplement.

There are two types of MSM:

  • Distilled Ultra-Pure MSM – The gold standard, made using a 4-step distillation process for the purest form.
  • Pure-Crystalline MSM – Created through a centrifuge process, maintaining high purity while being slightly more affordable.

Every batch is independently tested to ensure zero additives, fillers, or anti-caking agents.

Click here for a detailed explanation of how MSM is manufactured.

What is the science of MSM?

Sulfur is essential for keeping your skin firm, joints flexible, and connective tissue strong. MSM provides a natural source of sulfur, helping your body produce collagen and elastin—the key proteins that keep skin smooth and resilient. Nearly half of your body's sulfur is found in your skin, muscles, cartilage, and bones, making it crucial for overall strength and mobility.

Click here for more information on The Science of MSM

    Is MISMO MSM listed with the TGA (Therapeutic Goods Administration)?

    Yes, click here to view the TGA listing for MISMO MSM

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