How Does MSM Promote Collagen and Keratin Production?

How Does MSM Promote Collagen and Keratin Production?

MSM is an organic sulfur compound, found naturally in plants, animals, and even humans, has been gaining recognition for its remarkable ability to promote collagen and keratin production – two essential proteins that play crucial roles in maintaining our youthful appearance and general well-being.

MSM and Collagen

Collagen is often referred to as the "glue" that holds our bodies together. It is the most abundant protein in the human body, providing structural support to our skin, bones, tendons, and cartilage. As we age, our body's ability to produce collagen reduces significantly, leading to wrinkles, joint pain, and other age-related issues. MSM is a one-stop-shop for counteracting these effects and here's why.

MSM works by providing the necessary sulfur compounds required for collagen synthesis. Sulfur is an essential mineral for the formation of disulfide bonds, which are crucial for the stability and strength of collagen fibers. By increasing the body's sulfur levels, MSM can enhance collagen production, leading to healthier, more youthful-looking skin, stronger bones, and improved joint health.

MSM and Keratin

While collagen is the glue that holds us together, keratin is the protein that gives our hair, nails, and skin their strength and resilience. Like collagen, keratin production also requires sulfur compounds, which MSM can provide in abundance.

Hair and Keratin

Hair is composed of 95% keratin, a fibrous, helicoidal protein that is a component of the skin and its appendages, including the hair and nails. It is synthesized by keratinocytes and is insoluble in water, which helps to protect the hair and contributes to its impermeability.

The hair contains 18 amino acids, including proline, threonine, leucine, and arginine. Keratin is particularly rich in cysteine. Cysteine is a sulfurated amino acid that forms disulfide bonds between molecules and thus lends the structure strength and resistance. Aging and excessive exposure of hair to solar irradiation cause dryness, reduced strength, a rough surface texture, loss of color, decreased luster, stiffness, brittleness, and an overall dull, unhealthy appearance.

Studies have shown that MSM can improve keratin production, resulting in stronger, healthier hair and nails that are less prone to breakage and splitting. MSM works by providing the necessary sulfur compounds for keratin synthesis, enabling the formation of disulfide bonds that contribute to the strength and durability of keratin fibers.

Nails and Keratin

Nails are composed of a protective protein called alpha-keratin, which imparts tough rigidity. Nails get their strength from 3 linked keratin layers, where oils and moisture cement and lubricate the nail plate. Functionality results from the nail shape, which mirrors that of the underlying bone. Hair and nails that maintain tight inter-corneocyte connections are generally not subject to desquamation. However, hair is shed through life-cycle programming, and nail corneocytes are eroded due to friction and physical activity.

"MSM may donate sulfur to keratin, which could help strengthen the bonds between keratin molecules in the hair and nails."

By promoting collagen and keratin production, MSM offers a range of potential benefits that extend far beyond just healthy skin and hair:

  1. Improved Skin Health: Increased collagen production can lead to firmer, more elastic skin with fewer wrinkles and fine lines, giving you a radiant, youthful glow.
  2. Stronger Bones and Joints: Collagen is essential for maintaining bone density and joint health, reducing the risk of osteoporosis and joint degeneration. With MSM supporting collagen production, you can enjoy greater mobility and flexibility as you age.
  3. Healthier Hair and Nails: Boosted keratin production can result in stronger, more resilient hair and nails, reducing breakage and promoting growth. Say goodbye to split ends and brittle nails!
  4. Faster Wound Healing: Collagen plays a crucial role in the wound healing process, and increased collagen production can accelerate tissue repair, helping you recover from injuries more quickly.
  5. Reduced Inflammation: MSM has been shown to possess anti-inflammatory properties, which can help alleviate joint pain, muscle soreness, and other inflammatory conditions.

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MISMO MSM - 440g / Ultra-Pure Distilled - Pain Relief
MISMO MSM - Pain Relief
MISMO MSM - Capsules / Ultra-Pure Distilled - Pain Relief
MSM capsules pain relief
MISMO MSM - 440g / Pure Crystalline - Pain Relief
MISMO MSM - 850g Ultra-Pure Distilled - Pain Relief
MISMO MSM - 850g/ Pure Crystalline - Pain Relief
MISMO MSM - 2kg Ultra-Pure Distilled - Pain Relief
MISMO MSM - 2kg / Pure Crystalline - Pain Relief
MISMO MSM - Capsules / Ultra-Pure Distilled - Pain Relief
MISMO MSM - Capsules/ Ultra-Pure Distilled - Pain Relief


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What is MSM?

MSM (Methyl Sulphonyl Methane or Dimethyl Sulfone) is an organic sulphur compound found in all living organisms. It is the purest and most bio-available form of sulphur, one of the essential minerals crucial to life and the regeneration of cells. MSM has traditionally been taken as a food supplement to increase joint health for flexibility and mobility, as well as for strong hair and nails, beautiful skin, and other health conditions from leaky gut syndrome to mild arthritis, osteoporosis, and psoriasis. 

Why do we need to supplement with MSM?

Natural MSM is largely destroyed when our food is processed and can be lost entirely when foods and ingredients are stored for a long period of time. MSM bonds with moisture, so any food which undergoes any sort of dehydration will lack its natural MSM.

For these reasons, and because MSM is so critical for almost every athletic function in active bodies, it is important to consistently supplement with a quality MSM nutritional supplement 

What is the science of MSM?

Sulphur is integral to the production of collagen and elastin, and MSM is a source of organic Sulphur. Collagen is the principal structural protein holding the skin together and is largely responsible for the skin’s mechanical properties.  Approximately half of the body's sulphur content is found in the skin, muscles, cartilage and bones.

Click here for more information on The Science of MSM

How can MSM benefit your skin, hair and nails?

  • Protecting collagen against collagen degrading enzymes
  • Reducing fine lines and wrinkles by boosting collagen and elastin production
  • Boosting the natural production of Glutathione, one of the body's key anti-oxidants ... as an anti-oxidant, MSM will boost the immune system and reduce pigmentation and cellular damage
  • Acting as an anti-inflammatory agent by reducing the production of cytokines (compounds that cause inflammation)
  • Maintaining skin cell membrane flexibility and permeability, promoting an efficient exchange of nutrients and waste products to help keep skin clear
  • Helping to maintaining the body's pH balance

How can MSM help with joint health and support? 

MSM has powerful anti-inflammatory properties and can be used as a natural alternative to help reduce pain from mild arthritis and osteoarthritis related symptoms.

How does MISMO MSM help with exercise recovery?

Our muscles, skin, bones, organs, and connective tissue all rely on sulphur and without it our bodies can not function properly.  MSM is an important nutritional supplement for anyone living an active lifestyle, as it delivers the sulphur and methyl nutrients which are key to the structure of healthy cells in muscle and connective tissue.

MSM is valued by bodybuilders, strength, and power athletes because it supports healthy and flexible cell structures and can help reduce the inflammation of muscle tissue and can offset muscle soreness and joint pain caused by inflammation.

Where is MSM found and how is it manufactured?

MSM is found in the fluid and tissue of all living organisms. It is present in a variety of foods including raw vegetables, eggs, milk and fish, but is lost through cooking and food processing. One of the richest natural supplies is pine trees and cabbage.

Although MSM is abundant in nature, even the richest natural sources only provide MSM in the level of several parts per million. Commercial extraction of MSM from trees is not possible so a process is undertaken which parallels the natural oxidation that occurs in the marine atmosphere and produces MSM that is a chemical compound identical to that found in nature.

Click here for a detailed explanation of how MSM is manufactured.

What is the difference between Distilled Ultra-Pure MSM and Pure-Crystalline MSM?

With the distilled product, the MSM solution is heated up to a point where the MSM is released as a vapour and the pure crystals are formed and harvested as the vapour cools on the inside surface of a distillation column.  The heating-up of the MSM solution and the subsequent cooling and harvesting process requires a lot more energy, and hence the reason why the price is a bit higher.

With the crystalline product, the MSM solution is "spun" at super-high speed in a centrifuge and the MSM crystals are formed on the walls of the centrifuge.  And although the MSM solution is highly-pure before the crystallisation process begins (having undergone a reverse-osmosis filtration process), there is a remote possibility that if there are any trace impurities in the solution they can become encapsulated in the crystalline structure.

How pure is MISMO MSM?

Every batch of our MSM is rigourously tested by an independent laboratory to ensure the highest possible quality with no additives or anti-caking agents. MSM is gluten free and vegan / vegetarian. Packaged in Australia from imported ingredients.

    How much MISMO MSM should I be taking?

    An average dose is between 2 to 6 grams daily. Most people take a teaspoon (approx. 4 grams) daily. If more relief is needed, increase the dose slowly. Can be taken in water or juice after breakfast, although there are no rules as to when you should take MSM.

    It is recommended to take MSM in the morning, as it can give a boost of energy. Side effects when starting out with MSM can be nausea and/or headaches. This is not uncommon and is linked to the detoxifying benefits of MSM. We recommend lowering your dose if experiencing these symptoms and gradually increasing with time.

    WARNINGS: If taking strong blood thinners, do not take MSM without your doctor's approval. Not to be taken by children without a health professional's advice.  MSM can also interfere with the accuracy of the blood test for liver enzymes by sometimes producing false positive results. It is recommended you cease taking MSM at least 4 days before these blood tests. You can resume after the test.

    Is MISMO MSM listed with the TGA (Therapeutic Goods Administration)?

    Yes, click here to view the TGA listing for MISMO MSM


      Customer Reviews

      Based on 301 reviews
      Joan Wakely

      Great service

      Tabatha Turner
      Pain free!

      I recently discovered i might have Endo and am booked in for all the relevant tests. I started taking MSM two weeks before my cycle and when it hit, the pain was halved if not completely gone. I am in shock! I am going to test it out for another cycle to see if it was the reason, however after some research I can already see that it greatly helps with endo. World changing!

      Kay Blair

      I am really pleased with my orders from mismo especially the msm thank you for great products

      This is just what I need

      MISMO MSM does help! We take it daily.

      Ruth Dyer
      Great stuff

      I have been taking MSM for many years now, and it certainly keeps my arthritis under control.